A Table of all published GWAS with proteomics

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Here you find all published genome-wide association studies with multiplexed protein traits in blood (pGWAS). If a study is missing from this list, please let me know.

This table was initially published as Supplementary Table 1 in Suhre et al. (2017) and has been updated as of September 04, 2018.

ReferenceStudy population#Samples in study#Proteins assayed#pQTLs reportedPlatform type
Melzer et al. (PLoS Genet, 2008)Population study1200428Immuno-assay
Lourdusamy et al. (Hum Mol Genet, 2012)Elderly Europeans9677860Aptamer-based
Johansson et al. (PNAS, 2013)Two population cohorts10601635Mass-spectrometry
Kim et al. (PLoS One, 2013)Altzheimer's disease cohort52113228Immuno-assay
Enroth et al. (Nature Comm, 2014)Population study9707718Immuno-assay
Kauve et al., PLoS Genet., 2014CSF fluid from two Altzheimer's disease cohorts574595Immuno-assay for proteins relevant to Altzheimer's disease
Liu et al. (Mol Syst Biol, 2015)Female twins11334218Mass-spectrometry
Deming et al. (Sci Rep, 2016)Alzheimer cohort81814656Immuno-assay
Solomon et al. (Circ Cardiovasc Genet, 2016)Population study3305127Immuno-assay for proteins implicated in cardiovascular diseases
Ahola-Olli et al. (Am J Hum Genet, 2017)Population study82934827Immuno-assay for cytokines and growth factors
Di Narzo et al. (PLoS Genet, 2017)Inflammatory bowel disease (IBD) patients187112841Aptamer-based
Suhre et al. (Nature Comm, 2017)KORA and QMDiab study (Germany and Qatar)13351124539Aptamer-based
Sasayama et al. (Hum Mol Genet, 2017)CSF fluid from a Japanese population1331126476Aptamer-based
Folkersen et al. (PLoS Genet., 2017)Population study33948379Immuno-assay for proteins implicated in cardiovascular diseases
Ahsan et al. (PLoS Genet., 2017)Population study103312145Antibody-based proximity extension assay
Carayol et al. (Nature Comm, 2017)Obese subjects494112955Aptamer-based
Benson et al. (Circulation, 2017)Framingham Heart Study and Malmö Diet and Cancer Study21801129161Aptamer-based, array based genotyping and exome seq
Patin et al. (Nature Immunology, 2018)unrelated, Western European ancestry, Milieu Intérieur cohort10008736Mean fluorescence intensity (MFI), cell surface marker
Sun et al. (Nature, 2018); pre-print on bioRxivInterval study (UK blood donors)330129941927Aptamer-based
Emilsson et al. (Science, 2018)AGES Reykjavik study (Islanders over 65)5457 41371957Aptamer-based
Yao et al. (Nature Comm, 2018); pre-print on bioRxivFramingham Heart Study 686171105Immuno-assay for proteins implicated in cardiovascular diseases, replication aptamer-based