Some time ago I asked a number of friends and collaborators to write a chapter on their favorite topic for an edited Springer book on metabolomics. This is the result … Enjoy !
Unlike previous books published on metabolomics, this book switches the focus from experimental questions and technical challenges, to the application of metabolomics with an emphasis on the underlying genetics. The chapters provide a thorough basis for the understanding of the underlying experimental techniques, concepts and potential biomedical applications of this exciting field. The interdisciplinary approach of this book addresses a wide readership, and contains educational aids for anyone not familiar with a particular area of metabolomics. The area of research where genetics and metabolomics meet is likely to represent a field where systems biology shall prosper highly in the years to come.
Source: Genetics Meets Metabolomics: from Experiment to Systems Biology, Springer, 2012. ISBN: 1461416884.
Table of Content
Pre-conditions for High Quality Biobanking in Large Human Epidemiological Cohorts for Metabolomics and Other – Omics Studies
Assay Tools for Metabolomics
Statistical Methods in Genetic and Molecular Epidemiology and Their Application in Studies with Metabolic Phenotypes
Ultrahigh Resolution Mass Spectrometry Based Non-targeted Microbial Metabolomics
Metabolomic Systems Biology of Protozoan Parasites
Mouse Genetics and Metabolic Mouse Phenotyping
Metabolomics in Animal Breeding
Metabolomics Applications in Human Nutrition
Metabolomics for the Individualized Therapy of Androgen Deficiency Syndrome in Male Adults
Systems Biology Resources Arising from the Human Metabolome Project
Understanding Cancer Metabolism Through Global Metabolomics
Genetic and Metabolic Determinants of Fatty Acid Chain Length and Desaturation, Their Incorporation into Lipid Classes and Their Effects on Risk of Vascular and Metabolic Disease
Mapping Metabolomic Quantitative Trait Loci (mQTL): A Link Between Metabolome-Wide Association Studies and Systems Biology
Metabolic Traits as Intermediate Phenotypes
Genome-Wide Association Studies with Metabolomics
Systems Biology Meets Metabolism